Official logo and claim of anti-wrinkle active ingredient ARGIRELINE® peptide, by Lipotec

A breakthrough in cosmetic technology as an alternative to well-known cosmetic procedures, topically targeting the same wrinkle-formation mechanism in a very different way.

  • ARGIRELINE® peptide (Acetyl Hexapeptide-8) is a replica of the N-terminal end of SNAP-25 and competes in vitro with the natural protein for a position in the SNARE complex.
  • Science. The formation of the SNARE protein complex is essential for the acetylcholine release at the synapsis, the neurotransmitter involved in muscle contraction.


Nothing is more attractive
than a relaxed face

Effect appears
in just 1 week

As demonstrated in vivo, a cream with 2% ARGIRELINE® peptide solution decreased appearance of wrinkles: volume diminished by 20.6% and length by 15.9%, on average, with statistically significant results. Other parameters used to describe wrinkles, like roughness and depth, were also decreased as proved in further clinical studies.

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In vivo efficacy results showing the effect of Lipotec’s ARGIRELINE® peptide on wrinkle volume and length
In vivo efficacy results showing the effect of Lipotec’s ARGIRELINE® peptide on wrinkle volume and length

Images of the expression wrinkles of a volunteer before and after 7 days.

A recognized cosmetic solution for early fine lines

"The number of wrinkles decreased after treatment and the existing ones were less deep, especially in the area around the eyes"Victoria Moral, 43 years

"The reduction of expression wrinkles was notorious for me and for those around me."Pilar Soriano, 56 years

"I noticed my skin more elastic and the crow's feet decreased visibly. I am delighted!"Maria José López, 48 years

around the world

Did you know…?
… that ARGIRELINE® peptide


Lipotec develops active ingredients for the personal care industry and supplies them to leading cosmetic product manufacturers and brand owners worldwide.

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