LEUPHASYL® peptide

Target achieved: smooth and young skin for longer

This pentapeptide is an alternative to fight against expression lines acting through calcium, by imitating enkephalins. It is compatible with other anti-wrinkle peptides for a synergistic effect.

Mechanism of action

It couples to the enkephalin receptor and closes the calcium channels. Thus it inhibits the release of acetylcholine in the synapse, reducing muscle contraction.

Cosmetic Benefits

Muscles remain in rest and the formation of wrinkles and expression lines is curbed. The face is smoother and the skin looks younger. In combination with ARGIRELINE® peptide, this advanced duo of peptides decreased the depth of wrinkles by 25%, raising values up to 47%, in 1 month.


*Natural / Derived natural ingredient (ISO 16128)


Lipotec develops active ingredients for the personal care industry and supplies them to leading cosmetic product manufacturers and brand owners worldwide.

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